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SNS-032 br User knowledge representation Various representat
2020-09-17
User knowledge representation Various representation approaches of user interests and preferences are proposed. In this work, we advocate a multidimensional semantic approach based on Bouzghoub et al. meta-model (Bouzeghoub and Kostadinov, 2005), depicted in Fig. 6, to model the user profile. The
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It should also be noted that
2020-09-17
It should also be noted that remarkable individual differences in extinguished fear bradycardia (i.e., CS+E vs. CS−E) during initial Day 2 recall test were observed, particularly within Met carriers. Exploratory analyses revealed that these individual differences were partly driven by the level of r
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br Materials and methods br Results br Discussion
2020-09-17
Materials and methods Results Discussion One novel finding in our study is that CK2 inhibition preserved axon function and structure in WM against ischemia. Consistent with these findings, oligodendrocytes, astrocytes, myelin, and VU 0364439 receptor were found to express CK2α. The robust
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br Materials and methods br Data and statistical
2020-09-17
Materials and methods Data and statistical analysis The results were expressed as mean ± SEM. One-way analysis of variance (ANOVA), followed by Bonferroni\'s post-test or unpaired Student\'s t-test were used to determine significant differences between groups. The program used for statistical
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Studies have recently raised concerns about the potential
2020-09-17
Studies have recently raised concerns about the potential role of parabens in breast cancer, as these chemicals are commonly detectable in human breast cancer tissues. An analysis of 160 breast tissue samples collected from 40 mastectomies for primary breast cancer in England showed that at least on
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cAMP mediated signaling pathways are important for maintaini
2020-09-17
cAMP-mediated signaling pathways are important for maintaining metabolic homeostasis, and the effects of the glucagon/catecholamine–cAMP–PKA axis on energy balance have been well documented [20]. For example, PHA-767491 of the PKA 2β regulatory subunit (RIIβ) in mice leads to increased expression o
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br Materials and methods br Results
2020-09-17
Materials and methods Results Discussion The EP4 Gastrodin for PGE2 is similar to the EP1, EP2 and EP3 receptors in that they all have seven transmembrane segments and are coupled to Gα subunits of heterotrimeric G proteins, with a different Gα subunit for each receptor (Sugimoto and Narum
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Accordingly we prepared three compounds and as shown in
2020-09-17
Accordingly, we prepared three compounds (, , and ) as shown in . Condensation of commercially available Ac-DEVD-pNA with glycine methyl ester gave amide . A Friedel–Crafts reaction between compound and 4-methyl valeryl chloride in the presence of aluminum chloride mainly produced undesired comp
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We should also note that although
2020-09-16
We should also note that, although AOAA is not a specific H2S inhibitor, its inhibitory effect on l-cysteine-induced relaxations are related to H2S since addition of AOAA to another H2S inhibitor PAG did not provide a further inhibition of these relaxations in penile tissue [37]. In our study, the c
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br Materials and methods br Results br
2020-09-16
Materials and methods Results Discussion The investigation of oxysterols is highly complex and challenging, arising not only from the large number of molecules in this family, but also due to their low abundance in biological systems compared to cholesterol and their susceptibility for auto
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Additionally we analysed the features of apomict
2020-09-16
Additionally, we analysed the features of apomict and sexual Boechera species DNMT proteins. All DNMT proteins showed highly similar theoretical pI, molecular weight and predicted sub-cellular localization (Table 2). Discussion Identification of the structure and expression levels of DNMTs durin
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br Materials and method br Results and discussion We
2020-09-16
Materials and method Results and discussion We carried out DNA ligation using free and immobilized T4 DNA ligase in the absence of a magnetic field at 16°C, where the enzyme concentration (final concentration after mixing the solutions for the reaction) in both cases was 0.40μg/mL, and found t
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br Introduction Diacylglycerol kinase DGK is a
2020-09-16
Introduction Diacylglycerol kinase (DGK) is a lipid-metabolizing enzyme that phosphorylates diacylglycerol (DG) to produce phosphatidic Annexin V-Cy5 Apoptosis Kit (PA) [[1], [2], [3], [4]]. DG and PA act as lipid second messengers in a wide variety of biological processes. Ten DGK isozymes (α, β
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br Experimental br Results and discussion br Conclusions In
2020-09-16
Experimental Results and discussion Conclusions In this work we presented the direct electrochemical behaviour of the Mo containing formate dehydrogenase, purified from D. desulfuricans, where the Mo centre redox features were observed. The results allowed to calculate the reduction potenti
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Contrary to genetic aberrations epigenetic
2020-09-16
Contrary to genetic aberrations epigenetic methylation markers with broad coverage of OvCa subtypes were detected in primary tumors [21]. Ibanez de Caceres et al. [22] identified hypermethylation of BRCA1, APC, p16, p14, DAPK or RASSF1A in 50 of 50 primary tumors. Moreover the methylation pattern wa
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