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Ultrasound is an acoustic wave with a frequency
2020-02-08

Ultrasound is an acoustic wave with a frequency >20 kHz that needs a medium to propagate [20]. Accompanied by the spread of an ultrasonic wave, a series of alternating cycles of compression and rarefaction emerge in the liquid medium. During the rarefaction cycle, microbubbles are formed because of
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Introduction The Bromeliaceae family is one of the most morp
2020-02-06

Introduction The Bromeliaceae family is one of the most morphologically and ecologically diverse flowering plant families native to the tropics and subtropics of the New World (Benzing, 2000). They comprise >3000 species and are traditionally divided into three subfamilies: Pitcairnioideae, Bromeli
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The Fontan circulation When first described in the Fontan op
2020-02-05

The Fontan circulation When first described in 1971, the Fontan operation ushered in a new paradigm in the care of children born with the varied forms of complex congenital bms-536924 disease (CHD) characterized by a single effective pumping chamber.1., 2. This procedure, which creates a total cav
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IL-4, murine recombinant Although BPA has been proven to cau
2020-02-05

Although BPA has been proven to cause many health issues such as obesity and neurological toxicity (Rubin, 2011), the effects and mechanisms of BPA on the human tumorigenesis and cancer development are still not well illustrated. In the present study, we found that 10 to 10M BPA significantly promot
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EphB promotes tumor growth by stimulating angiogenesis throu
2020-02-05

EphB4 promotes tumor growth by stimulating angiogenesis through EphrinB2 [18]. However, the distinct and specifically involvement of Amyloid Beta-peptide (25-35) and veins in the tumor angiogenesis of all tumor grades is unclear. Our results indicate that the relation between EphrinB2 and EphB4 sta
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Haj Yahya et al applied native chemical ligation for
2020-02-05

Haj-Yahya et al. [52] applied native chemical ligation for the construction of diubiquitin probes. They attached a cysteine residue to the lysine side chain of the proximal ubiquitin and ligated the distal module using the C-terminal thioester of ubiquitin. Elimination of the sulfur vuf australia r
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Indeed a significant difference was observed for the binding
2020-02-05

Indeed, a significant difference was observed for the binding of glycated α-synuclein. Thus, g-α-synuclein bound to other part of GAPDH in 4 of 10 simulations (Fig. 2F, brown, yellow and dark-green chains, and Fig. 2G, brown chain). This additional binding site is located on the interface between O
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DDR is characterized by an
2020-02-05

DDR2 is characterized by an N-terminal discoidin domain and a C-terminal kinase domain [7]. Characteristics of DDR1, which is a homologue of DDR2, have been extensively investigated in terms of expression level in cancer tissues and biological functions in normal and cancer cell conditions, but char
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N acetylation by N acetyltransferase NAT
2020-02-04

N-acetylation by N-acetyltransferase (NAT) is an important metabolic pathway for some substances, and there are 2 functional NAT isoforms in humans—NAT1 and NAT2. Studies of etamicastat in healthy subjects showed an extensive N-acetylation of etamicastat to the inactive metabolite BIA 5-961, and a l
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br Materials and methods br
2020-02-04

Materials and methods Results Discussion The present study shows that 1) overexpression of wild-type or mutant α-SYN interferes with forskolin-induced DBH up-regulation, 2) α-SYN enters into the nucleus and is able to bind to CRE region, compete for CREB, and attenuate CRE-mediated transcri
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TKI discontinuation studies demonstrate that a portion of
2020-02-04

TKI discontinuation studies demonstrate that a portion of TKI-treated CML patients remain in remission for up to 3 years, although long-term risk assessment is still necessary (Bansal and Radich, 2016). The majority of CML patients depend on lifetime TKI treatment, and substantial efforts have been
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A cocktail approach can detect the activities of
2020-02-04

A cocktail approach can detect the activities of multiple CYP 450 isoforms following administration of multiple CYP-specific substrates in a single experiment. Caffeine, losartan, omeprazole, dextromethorphan and midazolam are often used as substrates in “cocktail probes” of human cytochrome CYP1A2,
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After crown formation root development begins via the intera
2020-02-04

After crown formation, root development begins via the interaction between the Hertwig root sheath (HERS) and the dental papilla, which differentiates into odontoblasts and forms dentin and pulp. HERS is associated with the number of roots and their morphology . The stem cells from the apical papil
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Moreover in this study weak expression of MT
2020-02-04

Moreover, in this study, weak expression of MT1 and MT2 was also detected in the oviduct muscular layers. Although there are no reports regarding the role of MT1 and MT2 in oviduct muscular layers, previous studies have demonstrated that melatonin plays an important role in the uterine contractility
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perifosine This study was aimed to assess a number of estera
2020-02-04

This study was aimed to assess a number of esterase activities, namely erythrocyte AChE, plasma BuChE and BeChE, and serum PON1 towards a number of substrates, as well as the major genetic polymorphisms of BCHE and PON1in a cohort of greenhouse workers exposed to low toxicity pesticides under an int
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