• Bisphosphonates significantly reduce or prevent SREs

  2019-05-23

  

  Bisphosphonates significantly reduce or prevent SREs. The use of Zol for patients with bone metastases is currently the gold standard treatment [4]. However, it is still unclear whether Zol contributes to a survival benefit [9]. Niikura et al. recently reported that Zol did not prolong progression-f

• Welcome to volume two of the the

  2019-05-23

  

  Welcome to volume two of the , the first journal devoted to the multidisciplinary management of bone disease in cancer patients. During the past year, the importance of bone oncology in cancer care has continued to increase. This follows the emergence of further clinical data supporting the use of b

• Evidence of a variant induction of apoptosis to vorinostat i

  2019-05-23

  

  Evidence of a variant induction of apoptosis to vorinostat in different DLBCL cell lines according to HAT mutational status implies that defects in CREBBP/EP300 could potentially explain the heterogeneous observations in clinical trials of vorinostat in NHL. These findings, however, need to be confi

• br Discussion Prehabilitation is a program to

  2019-05-23

  

  Discussion “Prehabilitation” is a program to enhance functional capacity and psychological health to enable patients to withstand an upcoming stressor, e.g. surgery. It is intended to reduce treatment-related morbidity and/or mortality, to decrease length of hospital stay and/or re-admission, and

• Se trata de una generaci

  2019-05-23

  

  Se trata de una generación que creció ML 141 la sombra de un “experimento” como Poesía en movimiento, publicado por primera vez en 1966, pero que en 1990 había alcanzado la 21ª edición en Siglo XXI, antología que apostaba por la poesía de ruptura y el poema como signo (Escalante 2013: 91-94). En ci

• Dig-11-ddUTP br Introduction Magnetic resonance imaging MRI

  2019-05-23

  

  Introduction Magnetic resonance imaging (MRI) has great utility in evaluating musculoskeletal tumors. However, some lesions have an appearance on MRI that make it challenging to differentiate benign from malignant lesions. Even intravenous (IV) Dig-11-ddUTP sometimes does not allow differentiati

• Agosto toma la medida del relato hist rico

  2019-05-23

  

  Agosto toma la medida del relato histórico en algunas ocasiones, de la crónica periodística en otras, para obtener una narración que ha llegado a entremezclarse con la realidad, o al menos con una investigación académica bien documentada, al grado tal que es bastante común encontrarla citada en artí

• Given this proud history it is deeply concerning that newly

  2019-05-23

  

  Given this proud history, it ubiquitin conjugating enzyme is deeply concerning that newly elected President Donald J Trump, has, through an executive order in his fourth day in office, reinstated a Reagan-era prohibition on the disbursement of federal funding to non-governmental organisations (NGOs

• In recent years there has

  2019-05-22

  

  In recent years, there has been growing interest regarding the role of spliceosome machinery in neoplastic diseases following evidence of the involvement of splicing factor mutations in diverse cancers . (Serine-Arginine Splicing Factor 2) is a member of the serine/arginine (S/A) rich family pre-mRN

• Discussion Mantle cell lymphoma is a distinct type of mature

  2019-05-22

  

  Discussion Mantle cell lymphoma is a distinct type of mature B-cell neoplasm that accounts for approximately 3–10% of non-Hodgkin\'s lymphoma. It is referred to several aliases, such as lymphocytic lymphoma of intermediate differentiation, mantle zone lymphoma, centrocytic lymphoma. Diffusion of no

• Studies and reports of lung metastasis of GCTB are rare

  2019-05-22

  

  Studies and reports of lung SCR 7 of GCTB are rare because of the low incidence of lung metastasis. The biological behavior and clinical features of GCTB are difficult to predict [6,7]. Some researchers have attempted to analyze related clinical factors of lung metastasis, such as age, sex, primary

• Any abnormality causing a loss

  2019-05-22

  

  Any abnormality causing a loss-of-function in the IKs macromolecular complex may lead to adrenergic-induced imbalance in ventricular repolarization currents and consequent QTc prolongation, which is identified based on the defective response of IKs to PKA stimuli due to mutations in KCNQ1 (-G269S, -

• The most compelling apparent evidence in support of the

  2019-05-22

  

  The most compelling apparent evidence in support of the depolarization hypothesis derives from the seminal studies of Nademanee et al. [129]. showing that radiofrequency ablation (RFA) of epicardial sites displaying late potentials and fractionated bipolar electrograms in the RVOT of patients with B

• Assessment of the growth of children is fundamental to paedi

  2019-05-22

  

  Assessment of the growth of children is fundamental to paediatrics. Aberrations of growth, whether too little or too much, can be signs of current or past ill health, particularly in the case of poor growth, or portend later ill health, particularly with excessive weight gain. To know whether growth

• In summary Welch and colleagues review is

  2019-05-22

  

  In summary, Welch and colleagues\' review is important. Not all systematic reviews on the same topic reach the same conclusion, but the convergence between the Campbell and Cochrane reviews here could hardly be stronger. The additional network and subgroup analyses in the Campbell review find no evi

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